The endoscopic approach requires smaller incisions than traditional open surgery, typically measuring only 1-3 centimetres in length. This reduces tissue disruption and scar formation.
Endoscopic Peripheral Nerve Surgery

Dr Jacqueline Tan
MBBS (SG) | MRCS (Edin) | MMed (Surgery) | FAMS (Hand Surgery)
Endoscopic peripheral nerve surgery is a procedure that uses a small camera (endoscope) and specialised instruments to decompress or release trapped or compressed nerves in the upper extremity. This minimally invasive technique creates smaller incisions than traditional open surgery, allowing surgeons to visualise and access the affected nerve through a small tubular channel. The procedure aims to relieve pressure on peripheral nerves of the hand, wrist, and elbow, restore normal function, and reduce pain caused by nerve compression.


Indications for Endoscopic Peripheral Nerve Surgery
The following conditions may indicate a need for endoscopic peripheral nerve surgery when conservative treatments have not provided adequate relief.
- Carpal Tunnel Syndrome: This condition involves compression of the median nerve at the wrist, causing numbness, tingling, and weakness in the hand and fingers. When non-surgical treatments fail to alleviate symptoms, endoscopic release may be considered.
- Cubital Tunnel Syndrome: Compression of the ulnar nerve at the elbow causes this condition, resulting in numbness and tingling in the ring and little fingers. Persistent symptoms despite conservative management may necessitate surgical intervention.
Benefits of Endoscopic Peripheral Nerve Surgery
Endoscopic peripheral nerve surgery offers several advantages compared to traditional open surgical techniques for appropriate candidates.
Smaller Incisions
Reduced Post-operative Pain
Less tissue disruption generally results in less post-operative discomfort for patients. This can lead to a decreased need for pain medication during recovery.
Faster Recovery
Many patients experience shorter recovery times compared to traditional open procedures. This allows for an earlier return to daily activities and work in appropriate cases.
Enhanced Visualisation
The endoscope provides magnified views of the surgical area, allowing surgeons to see anatomical structures in detail. This helps with precise identification of the compressed nerve and surrounding tissues.
Surgical Techniques
Single-Portal Technique
This method uses one small incision through which both the endoscope and surgical instruments are introduced. A specialised portal system creates a working channel for the procedure. The single entry point maintains the minimally invasive nature of the surgery while allowing adequate visualisation and access to the compressed nerve. This technique is commonly used for carpal tunnel release as well as cubital tunnel release.
Two-Portal Technique
This approach utilises two separate small incisions: one for the endoscope and another for the surgical instruments. The dual-portal system provides improved manoeuvrability and visibility during more complex procedures.This technique may be employed for carpall tunnel release.
Preparing for the Procedure
Medical Evaluation
A comprehensive assessment is conducted before scheduling surgery to determine suitability for the procedure. This typically includes physical examination, medical history review, and nerve conduction studies to confirm the diagnosis and location of nerve compression. Imaging studies such as ultrasound or MRI may be ordered to evaluate the affected area in detail.
Medication Adjustments
Certain medications may need to be temporarily discontinued before surgery to reduce bleeding risk. Blood thinners such as aspirin, warfarin, or clopidogrel typically require special management, as do anti-inflammatory medications and some supplements.
Fasting Guidelines
Instructions regarding food and drink restrictions before surgery must be strictly followed. Typically, patients are advised not to eat solid food for 6 hours before the procedure. Clear liquids are permitted for up to 2-4 hours prior to surgery. Fasting may not be required for endoscopic carpal tunnel release, which can be performed under local or regional anaesthesia.
Step-by-Step Procedure
- Anaesthesia Administration: Local anaesthesia may be used alone or combined with intravenous sedation, depending on the specific procedure and patient factors. The anaesthetic is injected around the surgical site to numb the area completely. For more extensive procedures, regional anaesthesia that blocks nerve signals to the entire arm or general anaesthesia may be selected.
- Incision and Portal Placement: One or two small incisions (typically 1-2 cm) are made at predetermined locations. The exact positions depend on the nerve being treated and the specific endoscopic technique selected. Through these portals, a cannula (hollow tube) is carefully inserted to create a working channel.
- Endoscope Introduction: The endoscope, a thin tube with a camera and light source, is inserted through the cannula. This provides magnified visualisation of the surgical field on a monitor. The surgeon can clearly see the compressed nerve and surrounding structures in detail.
- Nerve Decompression: Using specialised instruments inserted alongside or through a separate portal, the surgeon removes or releases structures compressing the nerve. This may include cutting tight ligaments (such as the transverse carpal ligament in carpal tunnel syndrome), removing abnormal tissue growth, or dividing constricting bands.
- Closure and Dressing: After confirming successful decompression, the endoscope and instruments are removed. The small incisions are closed with sutures, surgical tape, or adhesive. A sterile dressing is applied to protect the wound. Depending on the procedure location, a splint or soft bandage may be added to limit movement and provide support during initial healing.
Post-Surgical Care and Recovery
Immediate Post-operative Care
Patients are monitored in the recovery area until the effects of anaesthesia subside. Pain management typically involves oral medications, and initial discomfort is expected. Elevation of the operated upper extremity helps reduce swelling in the first 24-48 hours.
Activity Restrictions
Specific limitations vary according to the nerve treated and individual factors. Generally, patients avoid heavy lifting, repetitive motions, and strenuous activities with the affected hand and arm for up to a month. Gradual return to normal activities follows as guided by the surgeon.
Hand Therapy
Specialised hand therapy may be prescribed to restore strength, dexterity, and function. This typically begins with gentle range of motion exercises and progresses to specific strengthening activities for the hand and upper extremity.
Potential Risks and Complications
Possible complications of endoscopic peripheral nerve surgery may include infection at the incision site, bleeding or haematoma formation, nerve injury resulting in increased numbness or weakness, incomplete decompression requiring revision surgery, and scar tissue formation around the nerve. Some patients may experience temporary increased pain during the healing process. Complex regional pain syndrome is an uncommon complication characterised by disproportionate pain and swelling in the hand and arm.
Frequently Asked Questions
How long does endoscopic peripheral nerve surgery take?
Most endoscopic nerve decompression procedures take between 30 and 60 minutes to complete. The exact duration depends on the specific nerve being treated, the complexity of the compression, and whether multiple nerves require attention.
When will I notice improvement after surgery?
Some patients report fast relief of certain symptoms, particularly pain related to nerve compression. However, symptoms like numbness and tingling may take weeks or months to resolve as the nerve heals. Motor function improvement typically occurs gradually over 3-6 months.
How soon can I use my hand after surgery?
Light use of the hand is often permitted within days of surgery, though this varies by procedure. Patients typically can perform basic activities such as eating and personal hygiene within a few days. Gradual increases in hand use follow during the recovery period.

Dr Jacqueline Tan
MBBS (SG)
MRCS (Edin)
MMed (Surgery)
FAMS (Hand Surgery)
Dr. Jacqueline Tan is a hand surgeon in Singapore with over 18 years of experience in managing hand, wrist, and nerve conditions. Formerly the Head of Department of Hand and Reconstructive Microsurgery at Singapore General Hospital, she has continued to contribute significantly to her profession.
- Director of Micro-Reconstruction Service and the Director of Peripheral Nerve and Paralytic Upper Limb Service
- Upon the completion of her training as a hand surgeon in Singapore, Dr Tan was awarded the prestigious Health Manpower Development Plan scholarship by the Ministry of Health (MOH).
- Completed a one-year advanced fellowship in Taiwan under the tutelage of internationally-acclaimed Hand and Orthopedic Microsurgeon – Professor Yuan-Kun Tu
- Dr Tan’s field of expertise is in early and late brachial plexus reconstruction, peripheral nerve disorders, reconstructive microsurgery of the extremities and wrist disorders.
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